U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.
Molekulargewicht:
872.06
CAS Nummer:
[124020-62-8]
Formel:
C40H73N9O12
Target-Kategorie:
HIV Protease
Anwendungsbeschreibung:
MCE Product type: Peptides
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