TRV055, CAS [[25849-90-5]]

Produktübersicht

• Artikelname: TRV055, CAS [[25849-90-5]]
• Artikelnummer: MCE-HY-P3136
• Hersteller Artikelnummer: HY-P3136
• Alternativnummer: MCE-HY-P3136-5MG,MCE-HY-P3136-10MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: TRV120055

Produktbeschreibung

TRV055 (TRV120055) is a G protein-biased agonist of angiotensin II type 1 receptors (AT1Rs). TRV120055 induces fibroblast proliferation, overexpression of collagen I and alpha-SMA, and stress fibre formation in human cardiac fibroblasts. TRV055 activates AT1 receptor/Galphaq-mediated signaling pathways, upregulates TGF-beta1 and p-ERK1/2. TRV055 induces collagen secretion in adult rat myofibroblasts at a level comparable to Ang II. TRV055 can be used to study the role of G protein-biased signaling of AT1Rs in regulating fibrotic responses[1][2].

Produkteigenschaften

• Molekulargewicht: 831.96
• Reinheit: 99.47
• CAS Nummer: [25849-90-5]
• Formel: C42H57N9O9
• Target-Kategorie: Angiotensin Receptor,ERK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides