Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 µM[1].
Molekulargewicht:
4062.35 (free acid)
Reinheit:
98.26
CAS Nummer:
[112844-49-2]
Formel:
C178H258N64O48.xC2HF3O2
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Peptides
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