Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the epsilonPKC specific inhibitor. Its inhibitory activity is based on epsilonPKC translocation and MARCKS phosphorylation. This peptide interferes with epsilonPKC interaction with the anchoring protein epsilonRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic gamma-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
Molekulargewicht:
947.11
Formel:
C40H70N10O14S
Target-Kategorie:
MARCKS,PKC
Anwendungsbeschreibung:
MCE Product type: Peptides
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