Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor with a Kd of 15 nM for Cav3.1 (alpha1G T-type) Ca2+ channel. Kurtoxin can interact with high affinity with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in central and peripheral neurons. Kurtoxin also shows cross-reactivity with voltage-gated Na+ channel[1].
Molekulargewicht:
7386.36
Formel:
C324H478N94O90S8
Target-Kategorie:
Calcium Channel,Sodium Channel
Anwendungsbeschreibung:
MCE Product type: Peptides
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