Vm24-toxin (TFA)

Produktübersicht

• Artikelname: Vm24-toxin (TFA)
• Artikelnummer: MCE-HY-P5917A
• Hersteller Artikelnummer: HY-P5917A
• Alternativnummer: MCE-HY-P5917A-25MG,MCE-HY-P5917A-1MG,MCE-HY-P5917A-10MG,MCE-HY-P5917A-50MG,MCE-HY-P5917A-5MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: Vaejovis mexicanus peptide 24 (TFA)

Produktbeschreibung

Vm24-toxin (Vaejovis mexicanus peptide 24) TFA, a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin TFA shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin TFA folds into a distorted cystine-stabilized alpha/beta motif consisting of a single-turn alpha-helix and a three-stranded antiparallel beta-sheet, stabilized by four disulfide bridges. Vm24-toxin TFA attenuates the CD4+ effector memory T cell response to T cell receptor (TCR) stimulation[1][2].

Produkteigenschaften

• Molekulargewicht: 3863.59 (free base)
• Reinheit: 97.86
• Formel: C157H253N51O45S9.xC2HF3O2
• Target-Kategorie: Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides