As an adapter protein, CRADD forms a PIDDosome complex with PIDD1 and CASP2, activates CASP2 and initiates apoptosis. It also recruits CASP2 to the TNFR-1 signaling complex in the tumor necrosis factor-mediated pathway, interacting with RIPK1 and TRADD. CRADD Protein, Human is the recombinant human-derived CRADD protein, expressed by E. coli , with tag free.
Molekulargewicht:
Approximately 21 kDa,based on SDS-PAGE under reducing conditions.
Formel:
8738(Gene_ID)P78560 (M1-E199)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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