CD300a/LMIR1 Protein, an inhibitory receptor, potentially diminishes cytolytic activity in NK cells and suppresses mast cell degranulation. It serves as a negative regulator in MYD88-mediated TLR signaling, activating PTPN6 but not TRIF. Upon tyrosine phosphorylation, CD300a/LMIR1 engages with PTN6/SHP-1, PTPN11/SHP-2, and INPP5D, showcasing its multifaceted involvement in immune regulation and cellular responses. CD300a/LMIR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD300a/LMIR1 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
45-50 kDa
Reinheit:
95.00
Formel:
/(Gene_ID)A0A7N9CE79 (L18-Q178)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten