The Nogo receptor/NgR protein functions as a multifunctional receptor for RTN4, OMG, and MAG, expanding its recognition to include the sialylated gangliosides GT1b and GM1, chondroitin sulfate proteoglycans, and heparin. NGFR coreceptor activation initiates Rho-mediated reorganization of the actin cytoskeleton, resulting in inhibition of axonal growth. Nogo Receptor/NgR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Nogo Receptor/NgR protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 60-73 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
102139327(Gene_ID)Q9N0E3 (C27-S447)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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