BID Protein, a pro-apoptotic member of the Bcl-2 family, is initially discovered through binding to both pro-apoptotic Bax and anti-apoptotic Bcl-2. BID is activated in the BCL-2-regulated or mitochondrial apoptosis pathway and acts as a switch between the extrinsic and intrinsic cell death pathways. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. BID Protein, Mouse (His) is the recombinant mouse-derived BID protein, expressed by E. coli , with C-His labeled tag.
Molekulargewicht:
Approximately 22.72 kDa
Reinheit:
95
Formel:
12122(Gene_ID)EDK99650.1 (A1-S195)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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