CDK12-CCNK Heterodimer Protein, Human (Active, sf9, GST, FLAG),Human,Sf9 insect cells
The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets Ser-5 phosphorylated at Ser-7 in the CTD repeat and can also target Ser-2. CDK12-CCNK Heterodimer Protein, Human (sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK12-CCNK Heterodimer protein, expressed by sf9 insect cells , with N-Flag, N-GST labeled tag.