The USP16 protein is a specific deubiquitinase that targets Lys-120 of histone H2A (H2AK119Ub), a tag associated with epigenetic transcriptional repression. By catalytically removing this ubiquitin moiety, USP16 acts as a coactivator, promoting subsequent phosphorylation of histone H3 (H3S10ph) Ser-11 to achieve mitotic chromosome segregation. USP16 Protein, Human (sf9) is the recombinant human-derived USP16 protein, expressed by sf9 insect cells , with tag free.
Molekulargewicht:
Approximately 100 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
80
Formel:
10600(Gene_ID)Q9Y5T5 (G2-L823)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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