Wee1 Protein, Human (sf9, His),Human,Sf9 insect cells
Wee1 Protein acts as a crucial negative regulator of the G2 to M transition, ensuring nuclear protection by phosphorylating CDK1 on Tyr-15 and inactivating the cyclin B1-CDK1 complex. Its peak activity in G2 phase decreases as cells progress into M phase, with dynamic regulation, increased phosphorylation during S and G2 phases, and diminished levels during M/G1 phase transition potentially due to degradation. Wee1 Protein, Human (sf9, His) is the recombinant human-derived Wee1 protein, expressed by sf9 insect cells , with N-8*His labeled tag.
Molekulargewicht:
Approximately 34 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
98.00
Formel:
7465(Gene_ID)P30291 (M291-K575)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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