PAK6, a dynamic serine/threonine kinase, regulates gene transcription activated by AR or MAP2K6/MAPKK6. It phosphorylates and inhibits AR-mediated transcription, hindering ESR1-mediated transcription. PAK6 interacts with IQGAP1, suggesting a role in cytoskeleton regulation. Moreover, it protects cells from apoptosis by phosphorylating BAD, showcasing its multifaceted impact on transcriptional control and cytoskeletal dynamics. PAK6 Protein, Human is the recombinant human-derived PAK6 protein, expressed by E. coli , with tag free.
Molekulargewicht:
Approximately 33.2 KDa.
Reinheit:
98
Formel:
106821730(Gene_ID)Q9NQU5 (G383-Y674)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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