LILRB1/CD85j/ILT2, Human (HEK293, Fc)

Produktübersicht

• Artikelname: LILRB1/CD85j/ILT2, Human (HEK293, Fc)
• Artikelnummer: MCE-HY-P70182
• Hersteller Artikelnummer: HY-P70182
• Alternativnummer: MCE-HY-P70182-50UG,MCE-HY-P70182-10UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: LILRB1/CD85j/ILT2 Protein, Human (HEK293, Fc),Human,HEK293

Produktbeschreibung

LILRB1/CD85j/ILT2 Protein is an inhibitory receptor broadly expressed on leukocytes. LILRB1 recognises a wide range of classical HLA-class I allelic variants, as well as the non-classical molecules HLA-F and -G by binding to the conserved a3 domain. LILRB1 also recognises the human CMV-encoded MHC class I homologue UL18. LILRB1 is encoded within the leukocyte receptor complex on 19q13.4. LILRB1 can function as a negative regulator of BiTE molecule-induced tumor cell killing. LILRB1 acts as a novel checkpoint inhibitory molecule capable of restricting BiTE molecule-mediated CD8+ T cell effector function[1][2][3][4]. LILRB1/CD85j/ILT2 Protein, Human (HEK293, Fc) is the recombinant human-derived LILRB1/CD85j/ILT2 protein, expressed by HEK293 , with C-hFc labeled tag.

Produkteigenschaften

• Molekulargewicht: 100-120 kDa
• Reinheit: 98
• Formel: 10859(Gene_ID)D9IDM8 (G24-H458)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins