IFN-lambda 1 (IL-29) is a member of the Type-III interferon family. IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFNlambda receptor 1 (IFNLR1) and IL-10 receptor subunit-beta (IL-10RB). When IFN-lambda 1 binds with the receptor complex, Jak1 and Tyk2 will be activated, and leads to subsequent tyrosine phosphorylation of the IFN-lambdaR1, and activation of STAT1 and STAT2[1]. IFN-lambda 1 modulates immunity in infections and autoimmune diseases[2]. IFN-lambda 1/IL-29 Protein, Human is a recombinant human IFN-lambda 1 (G20-T200) without any tag, which is produced in E. coli.
Molekulargewicht:
Approximately 19.8 kDa
Reinheit:
97
Formel:
282618(Gene_ID)Q8IU54 (G20-T200)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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