IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways[1][4]. IL-1 alpha protein, Human is a recombinant protein consisting of 159 amino acids (S113-A271) and is produced by E. coli.
Molekulargewicht:
Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
98
Formel:
3552(Gene_ID)P01583 (S113-A271)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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