CDK12-CCNK Heterodimer, Human (658-1490, sf9, GST) Preis auf Anfrage
Artikelnummer:
MCE-HY-P702885
Hersteller Artikelnummer:
HY-P702885
Alternativnummer:
MCE-HY-P702885-10UG
Hersteller:
MedchemExpress
Kategorie:
Proteine/Peptide
Alternative Synonym:
CDK12-CCNK Heterodimer Protein, Human (658-1490, sf9, GST),Human,Sf9 insect cells
The CDK12 protein is a cyclin-dependent kinase that critically phosphorylates the C-terminal domain of POLR2A, thereby regulating transcription elongation. It selectively targets Ser-5 phosphorylated at Ser-7 in the CTD repeat and can also target Ser-2. CDK12-CCNK Heterodimer Protein, Human (658-1490, sf9, GST) is the recombinant human-derived CDK12-CCNK, expressed by Sf9 insect cells, with N-GST labeled tag.
Molekulargewicht:
Approximately 90 kDa (CCNK) & 115-120 kDa (CDK12),based on SDS-PAGE under reducing conditions.