KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3s association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, His) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-6*His labeled tag.
Molekulargewicht:
Approximately 35-50 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
3804(Gene_ID)P43628-1 (H22-H245)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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