The B7-H4 protein acts as a negative regulator and inhibits T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. Significant significance can be observed when expressed on tumor macrophages, cooperating with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity. Azide-labeled B7-H4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Azide-labeled B7-H4 protein, expressed by HEK293, with C-His labeled tag.
Molekulargewicht:
Approximately 55-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formel:
242122(Gene_ID)Q7TSP5-1 (L25-G257)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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