CD40L/CD154/TRAP Protein, a cytokine, acts as a CD40/TNFRSF5 ligand, stimulating T-cell proliferation and cytokine production. It also facilitates immunoglobulin class switching and binds to integrins ITGA5:ITGB1 and ITGAV:ITGB3. CD40-CD40LG signaling requires both integrins and the CD40 receptor, leading to cell-type dependent effects like B-cell activation, NF-kappa-B signaling, and anti-apoptotic signaling. CD40L/CD154/TRAP Protein, Rabbit (HEK293, His, Flag) is the recombinant rabbit-derived CD40L/CD154/TRAP protein, expressed by HEK293, with N-His and N-Flag labeled tag.
Molekulargewicht:
Approximately 50-55 kDa,based on SDS-PAGE under non-reduced conditions,due to the glycosylation.
Formel:
100358388(Gene_ID)G1SKP7 (G116-L261)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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