FGF-21 Proteinas, pivotal in promoting glucose uptake in adipocytes, induces SLC2A1/GLUT1 expression, not affecting SLC2A4/GLUT4, contingent on KLB. It significantly regulates systemic glucose homeostasis and insulin sensitivity, with direct KLB interaction via its C-terminus. Engagement with FGFR4 adds complexity to its molecular mechanisms, highlighting its role in orchestrating cellular responses beyond localized effects. FGF-21 Protein, Human (HEK293, His) is the recombinant human-derived FGF-21 protein, expressed by HEK293, with N-His labeled tag.
Molekulargewicht:
Approximately 25-28 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Reinheit:
90.00
Formel:
26291(Gene_ID)Q9NSA1 (H29-S209)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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