The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Human (HEK293, Fc) is the recombinant human-derived GFRAL protein, expressed by HEK293, with C-hFc labeled tag.
Molekulargewicht:
Approximately 70-90 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formel:
389400(Gene_ID)Q6UXV0 (S19-E351)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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