GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (HEK293, His) is the recombinant mouse-derived GFRAL protein, expressed by HEK293, with C-His labeled tag.
Molekulargewicht:
Approximately 45-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formel:
404194(Gene_ID)Q6SJE0-1 (Q20-G349)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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