Glypican-3/GPC3, Human (S495A, S509A, HEK293, His) Preis auf Anfrage

Artikelnummer: MCE-HY-P704639
Artikelname: Glypican-3/GPC3, Human (S495A, S509A, HEK293, His) Preis auf Anfrage
Artikelnummer: MCE-HY-P704639
Hersteller Artikelnummer: HY-P704639
Alternativnummer: MCE-HY-P704639-100UG
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Alternative Synonym: Glypican-3/GPC3 Protein, Human (S495A, S509A, HEK293, His),Human,HEK293
The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. Glypican-3/GPC3 Protein, Human (S495A, S509A, HEK293, His) is the recombinant human-derived Glypican-3/GPC3 protein, expressed by HEK293, with C-His labeled tag.
Molekulargewicht: Approximately 28-32 kDa, 42-45 kDa and 65-75 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formel: 2719(Gene_ID)P51654-1 (Q25-H559)(Accession)
Anwendungsbeschreibung: MCE Product type: Recombinant Proteins