Erythropoietin receptor/EpoR Protein, Human (Biotinylated, HEK293 , hFc-Avi),Human,HEK293
The EPOR Protein functions as a receptor for erythropoietin, mediating erythroblast proliferation and differentiation upon EPO stimulation. The heterodimer triggers the JAK2/STAT5 signaling cascade and, in certain cell types, activates STAT1, STAT3, and the LYN tyrosine kinase. Additionally, isoform EPOR-T acts as a dominant-negative receptor, modulating EPOR-mediated signaling pathways. Erythropoietin receptor/EpoR Protein, Human (Biotinylated, HEK293 , hFc-Avi) is the recombinant human-derived Erythropoietin receptor/EpoR protein, expressed by HEK293 , with C-hFc-Avi labeled tag.
Molekulargewicht:
Approximately 55-70 kDa, based on Bis-Tris PAGE under reducing conditions, due to the glycosylation.
