The TIMP-1 protein forms a one-to-one complex with the target metalloprotease, irreversibly inactivating it by binding to the catalytic zinc cofactor. It inhibits multiple MMPs, activates cell signaling through CD63 and ITGB1, and interacts with MMP1, MMP3, MMP10, and MMP13. TIMP-1 Protein, Human (HEK293, His) is the recombinant human-derived TIMP-1 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 27 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Reinheit:
95.00
Formel:
7076(Gene_ID)P01033 (C24-A207)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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