PPM1A is a multifunctional enzyme that negatively regulates multiple signaling pathways. It significantly attenuates TGF-beta signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export, and signal termination. PPM1A Protein, Human (His) is the recombinant human-derived PPM1A protein, expressed by E. coli , with C-6*His labeled tag.
Molekulargewicht:
Approximately 45.0 kDa
Reinheit:
98
Formel:
5494(Gene_ID)P35813-1 (G2-W382)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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