4-1BB (CD137, TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily[1]. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment[2]. 4-1BB is also involved in enhancing Nrf2 and NF-kappaB pathway mediated apoptosis of endothelial cells[3]. Human 4-1BB protein is a surface glycoprotein with a transmembrane domain (187-213 a.a.). 4-1BB/TNFRSF9 Protein, Human is the extracellular part (E19-S184) of 4-1BB protein, produced by E. coli with tag free.
Molekulargewicht:
Approximately 17.7 kDa
Reinheit:
95
Formel:
3604(Gene_ID)Q07011 (E19-S184)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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