The TIGIT protein plays a key role in immune regulation and binds with high affinity to the poliovirus receptor (PVR). This interaction induces an immunosuppressive environment by increasing IL10 secretion and decreasing IL12B secretion. TIGIT Protein, Human (HEK293, mFc) is the recombinant human-derived TIGIT protein, expressed by HEK293 , with C-mFc labeled tag.
Molekulargewicht:
Approximately 40-50 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Reinheit:
95
Formel:
201633(Gene_ID)Q495A1-1 (M22-P141)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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