TOLLIP plays a key role in IL-1 and Toll-like receptor signaling, recruiting IRAK1 to the IL-1 receptor complex and inhibiting IRAK1 phosphorylation. It connects the ubiquitin pathway to autophagy, serving as a ubiquitin-ATG8 linker for autophagic clearance of ubiquitin conjugates. TOLLIP Protein, Human (His) is the recombinant human-derived TOLLIP protein, expressed by E. coli , with C-6*His labeled tag.
Molekulargewicht:
Approximately 31 kDa, based on SDS-PAGE under reducing conditions.
Formel:
54472(Gene_ID)Q9H0E2-1 (A2-P274)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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