CD38 protein plays diverse roles, synthesizing key second messengers: cyclic ADP-ribose (cADPR) for glucose-induced insulin secretion and nicotinate-adenine dinucleotide phosphate (NAADP) as a calcium mobilizer.Its cADPR hydrolase activity adds to its versatility.Notably, CD38 also regulates osteoclastic bone resorption, likely by producing cADPR and initiating a calcium ion signal through ryanodine receptor activation.CD38 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD38 protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 67 kDa,based on SDS-PAGE under reducing conditions.
Formel:
25668(Gene_ID)Q64244 (W45-V303)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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