IL-10 Protein, a key immune regulator, mitigates inflammation by binding to its receptor (IL10RA/IL10RB), activating JAK1 and STAT2, leading to STAT3-mediated anti-inflammatory gene expression. IL-10 targets APCs, reducing pro-inflammatory cytokines and hindering antigen presentation. It controls macrophage inflammation through metabolic reprogramming. Existing as a homodimer, IL-10 interacts with IL10RA/IL10RB. IL-10 Protein, Pig is the recombinant pig-derived IL-10 protein, expressed by E. coli , with tag free.
Molekulargewicht:
Approximately 18.0 kDa
Reinheit:
98
Formel:
397106(Gene_ID)Q29055 (S19-N175)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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