IFN-lambda 3/IL-28B, Human (P.pastoris, His) Preis auf Anfrage

Produktübersicht

• Artikelname: IFN-lambda 3/IL-28B, Human (P.pastoris, His) Preis auf Anfrage
• Artikelnummer: MCE-HY-P73201
• Hersteller Artikelnummer: HY-P73201
• Alternativnummer: MCE-HY-P73201-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: IFN-lambda 3/IL-28B Protein, Human (P.pastoris, His),Human,P. pastoris

Produktbeschreibung

IFN-lambda 3 (IL-28B) is a member of the Type-III interferon family. IFN-lambda 3 has high similar 96% sequence identity with IFN-lambda 2 at the amino acid level. IFN-lambda 2 has antiviral antitumour and immunomodulatory activities[1]. IFN-lambda 2 signals through a heterodimeric receptor complex comprising IFNLR1 and IL-10RB. When binding to the receptor complex, Jak1 and Tyk2 will be activated, and leads to tyrosine phosphorylation of the IFN-lambdaR1 and activation of STAT1 and STAT2. Activated STAT1 and STAT2 together with IRF-9 form a trimeric transcription factor complex (ISGF3). The formed ISGF3 then translocate to the nucleus and promotes the production of IFN-stimulated genes (ISGs)[2]. IFN-lambda 3/IL-28B Protein, Human (P.pastoris, His) is a recombinant human IFN-lambda 3 (V18-V196) with C-terminal His tag, which is expressed in P.pastoris.

Produkteigenschaften

• Molekulargewicht: Approximately 21.3 kDa
• Formel: 282617(Gene_ID)Q8IZI9 (V18-V196)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins