LIGHT/TNFSF14, Human (HEK293, Fc)

Produktübersicht

• Artikelname: LIGHT/TNFSF14, Human (HEK293, Fc)
• Artikelnummer: MCE-HY-P73281
• Hersteller Artikelnummer: HY-P73281
• Alternativnummer: MCE-HY-P73281-10UG,MCE-HY-P73281-2UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: LIGHT/TNFSF14 Protein, Human (HEK293, Fc),Human,HEK293

Produktbeschreibung

LIGHT/TNFSF14 protein (CD258, TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type [1]. LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNgamma, triggering tumor apoptosis signal [2]. LIGHT/TNFSF14 is also involved in the dominant LTbetaR-NIK-p52 NF-kappaB pathway promoting the expression of inflammatory gene[3]. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection[4]. Human LIGHT/TNFSF14 Protein has 240 amino acids and a transmembrane domain (38-58 a.a.). LIGHT/TNFSF14 Protein, Human (HEK293, Fc) is the extracellular part (D74-V240) of human LIGHT/TNFSF14 Protein, produced by HEK293 cells, with a N-terminal hFc-tag.

Produkteigenschaften

• Molekulargewicht: Approximately 50 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 91.00
• Formel: 8740(Gene_ID)O43557 (D74-V240)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins