TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-alpha). TNFRSF1A is a STAT3 target gene that regulates the NF-kappaB pathway. TNFRSF1A activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. TNF RI/TNFRSF1A Protein, Mouse (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region with a Fc tag at the C-terminus[1].
Molekulargewicht:
Approximately 55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
