The TrkA protein is a receptor tyrosine kinase that is critical in central and peripheral nervous system development, regulating neuronal proliferation, differentiation, and survival. As a high-affinity NGF receptor, TrkA undergoes homodimerization and autophosphorylation upon ligand binding, activating downstream effectors (SHC1, FRS2, SH2B1, SH2B2, PLCG1) cascade. TrkA Protein, Rat (HEK293, Fc) is the recombinant rat-derived TrkA protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 92-102 kDa,based on SDS-PAGE under reducing conditions.
Formel:
59109(Gene_ID)P35739-1 (A33-P418)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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