The TIMP-1 protein forms a one-to-one complex with the target metalloprotease, irreversibly inactivating it by binding to the catalytic zinc cofactor. It inhibits multiple MMPs, activates cell signaling through CD63 and ITGB1, and interacts with MMP1, MMP3, MMP10, and MMP13. TIMP-1 Protein, Human (HEK293, Fc) is the recombinant human-derived TIMP-1 protein, expressed by HEK293 , with N-hFc labeled tag.
Molekulargewicht:
Approximately 45-55 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
95.10
Formel:
7076(Gene_ID)P01033 (C24-A207)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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