Transforming growth factor-beta 2 (TGF-beta2), an extracellular glycosylated protein, is a member of the TGF-beta superfamily. TGFbeta2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFbetaR1 and TGFbetaR2). TGF-beta2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development[1][2]. TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).
Molekulargewicht:
Approximately 13-16 kDa & 40-60 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.