TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF-beta-1) chain, which maintains TGF-beta-1 latency in the extracellular matrix. TGFB1 binds non-covalently to TGF-beta-1 and interacts with ''environmental molecules (LTBP1, LRRC32/GARP, LRRC33/NRROS) to regulate TGF-beta-1 activation. TGF beta 1/TGFB1 Protein, Canine (HEK293, His) is the recombinant canine-derived TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 53-60 kDa(TGFB1 + LAP), 38-45 kDa(LAP) and 15 kDa(TGFB1), based on SDS-PAGE under reducing conditions, due to the glycosylation.
Reinheit:
95.00
Formel:
403998(Gene_ID)P54831 (L30-S390)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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