LIGHT/TNFSF14, Mouse (sf9, His, solution)

Produktübersicht

• Artikelname: LIGHT/TNFSF14, Mouse (sf9, His, solution)
• Artikelnummer: MCE-HY-P73837A
• Hersteller Artikelnummer: HY-P73837A
• Alternativnummer: MCE-HY-P73837A-20UG,MCE-HY-P73837A-50UG,MCE-HY-P73837A-10UG,MCE-HY-P73837A-5UG,MCE-HY-P73837A-2UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution),Mouse,Sf9 insect cells

Produktbeschreibung

LIGHT/TNFSF14 protein (CD258, TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type [1]. LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNgamma, triggering tumor apoptosis signal [2]. LIGHT/TNFSF14 is also involved in the dominant LTbetaR-NIK-p52 NF-kappaB pathway promoting the expression of inflammatory gene[3]. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection[4]. Mouse LIGHT/TNFSF14 Protein has 239 amino acids and a transmembrane domain (38-58 a.a.). LIGHT/TNFSF14 Protein, Mouse (sf9, His, solution) is the extracellular part (D72-V239) of mouse LIGHT/TNFSF14 Protein in solution form, produced by Sf9 insect cells, with N-terminal His-tag.

Produkteigenschaften

• Molekulargewicht: Approximately 24 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 98
• Formel: 50930(Gene_ID)Q9QYH9 (D72-V239)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins