IL-23R Protein, critical in immune response, forms the interleukin-23 receptor by associating with IL12RB1. Binding to IL23, it activates T-cells, NK cells, and potentially macrophage/myeloid cells through Jak-Stat signaling. Associated with autoimmune diseases and tumorigenesis, IL-23R, in the presence of IL12RB1, forms a heterodimeric IL-23 receptor, interacting with JAK2 and activating STAT3. IL-23R Protein, Rat (HEK293, His) is the recombinant rat-derived IL-23R protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 60-90 kDa due to the glycosylation.
Reinheit:
95
Formel:
689932(Gene_ID)XP_003753958 (M1-D367)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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