CD8A is an important immune glycoprotein that acts as a coreceptor for class I MHC:peptide complexes, linking T cells to antigens presented by APCs. It interacts with TCR and MHC class I, recruits LCK kinase, and initiates multiple signaling pathways. CD8A-CD8B Heterodimer Protein, Mouse (HEK293, Flag-His) is a recombinant protein dimer complex containing mouse-derived CD8A-CD8B Heterodimer protein, expressed by HEK293 , with C-His, C-Flag labeled tag.
Molekulargewicht:
Approximately 32-38 kDa (CD8 beta) & 42-50 (CD8 alpha) kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
