The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (HEK293, His) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 39-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Reinheit:
98.80
Formel:
79679(Gene_ID)Q7Z7D3-1 (F29-A258)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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