ALK-7 is a type I receptor serine-threonine kinase mediate inhibitory as well as stimulatory signals for growth and differentiation by binding to members of the TGF-beta superfamily. ALK-7 combined with specific ligands, such as Nodal, activin B and growth differentiation factor (GDF), can activate Smads and other signaling pathways, thereby regulating cell proliferation, differentiation and apoptosis in various cells[1][2][3]. ALK-7 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 113 amino acids (M1-E113).
Molekulargewicht:
The recombinant human ALK-7 consists of 92 amino acids & hFc tag and predicts a molecular mass of 35.96 kDa. It migrates as an approximately 43-56 kDa band in SDS-PAGE under reducing conditions.
Reinheit:
97.00
Formel:
130399(Gene_ID)Q8NER5 (L22-E113)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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