4-1BB (CD137, TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily[1]. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment[2]. 4-1BB is also involved in enhancing Nrf2 and NF-kappaB pathway mediated apoptosis of endothelial cells[3]. Mouse 4-1BB protein is a surface glycoprotein with a transmembrane domain (188-208 a.a.). 4-1BB/TNFRSF9 Protein, Mouse (HEK293, Fc, solution) is the extracellular part (V24-L187) of 4-1BB protein, produced by HEK293 cells with C-terminal Fc-tag.
Molekulargewicht:
Approximately 60-70 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
98
Formel:
21942(Gene_ID)P20334 (V24-L187)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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