UNC5B is an important netrin receptor that mediates axonal repulsion during nervous system development and binds to DCC to trigger signaling pathways. It negatively regulates vascular branching in angiogenesis, inducing tip cell filopodia retraction. UNC5B Protein, Human (HEK293, hFc) is the recombinant human-derived UNC5B protein, expressed by HEK293 , with C-hFc labeled tag.
Molekulargewicht:
Approximately 66-70 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
97.1
Formel:
219699(Gene_ID)Q8IZJ1-1 (G27-P363)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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