SIGIRR protein negatively regulates the Toll-like pathway and IL-1R pathway by inhibiting the recruitment of TLR4.SIGIRR disrupts Il1R1 and IL1RAP heterodimerization through its extracellular domain.SIGIRR Protein, Mouse (HEK293, His-hFc) is the recombinant mouse-derived SIGIRR protein, expressed by HEK293 , with C-hFc, C-His labeled tag.
Molekulargewicht:
Approximately 20-40 kDa due to the glycosylation
Reinheit:
95
Formel:
24058(Gene_ID)Q9JLZ8 (M1-H117)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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