LOXL2 protein mediates post-translational oxidative deamination of lysine residues, leading to the formation of allysine. It specifically deaminates H3K4me3, inhibits TFIID-dependent transcription, represses E-cadherin, activates the IRE1-XBP1 pathway, and promotes cross-linking of extracellular matrix proteins. LOXL2 is involved in EMT, tumor progression, angiogenesis regulation, and chondrocyte differentiation. LOXL2 Protein, Human (CHO, His) is the recombinant human-derived LOXL2 protein, expressed by CHO , with C-His labeled tag.
Molekulargewicht:
Approximately 85.5 kDa
Reinheit:
95
Formel:
4017(Gene_ID)Q9Y4K0 (M26-Q774)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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