LAG-3 (lymphocyte activation gene 3) protein is an inhibitory receptor on antigen-activated T cells, which transmits inhibitory signals by binding to ligands such as FGL1. LAG-3 is associated with CD3-TCR at the immune synapse, hinders T cell activation, and may cooperate with PDCD1/PD-1 to act as a co-receptor for PD-1. LAG-3 Protein, Rat (HEK293, His) is the recombinant rat-derived LAG-3 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 55 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
297596(Gene_ID)Q5BK54 (G24-L442)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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